STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103481666Cytochrome C oxidase assembly factor 3a. (99 aa)    
Predicted Functional Partners:
LOC103464663
Cytochrome c oxidase assembly factor COX14.
   
 
 0.857
ndufa8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 
 0.653
surf1
SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
   
 
 0.578
COX1
Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
    
 
 0.543
cmc1
COX assembly mitochondrial protein.
   
 
 0.523
LOC103459661
Cytochrome c oxidase assembly factor 6.
   
  
 0.509
lamtor2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
   
    0.508
LOC103481358
Translational activator of mitochondrially encoded cytochrome c oxidase I.
    
 
 0.503
osgin2
Oxidative stress induced growth inhibitor family member 2.
      
 0.501
LOC103476923
Cytochrome c oxidase assembly homolog 15 (yeast).
    
 
 0.476
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.