ENSPREP00000015917 protein (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSPREP00000015917

EH domain-containing protein. (133 aa)

Predicted Functional Partners:

ap2m1

0.996

cenpj

0.995

synrg

0.995

LOC103479233

0.995

LOC103479878

0.995

eps15

0.995

LOC103464192

0.995

cep135

0.995

ap4b1

0.994

LOC103476383

0.994

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000015917	LOC103464192	ENSPREP00000015917	ENSPREP00000029167	EH domain-containing protein.	Uncharacterized protein.	0.995
ENSPREP00000015917	LOC103476383	ENSPREP00000015917	ENSPREP00000025820	EH domain-containing protein.	AP complex subunit beta.	0.994
ENSPREP00000015917	LOC103479233	ENSPREP00000015917	ENSPREP00000017318	EH domain-containing protein.	Uncharacterized protein.	0.995
ENSPREP00000015917	LOC103479878	ENSPREP00000015917	ENSPREP00000018152	EH domain-containing protein.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.995
ENSPREP00000015917	ap2m1	ENSPREP00000015917	ENSPREP00000020784	EH domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.996
ENSPREP00000015917	ap4b1	ENSPREP00000015917	ENSPREP00000008088	EH domain-containing protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.994
ENSPREP00000015917	cenpj	ENSPREP00000015917	ENSPREP00000001878	EH domain-containing protein.	Centromere protein J.	0.995
ENSPREP00000015917	cep135	ENSPREP00000015917	ENSPREP00000029668	EH domain-containing protein.	Centrosomal protein 135.	0.995
ENSPREP00000015917	eps15	ENSPREP00000015917	ENSPREP00000027199	EH domain-containing protein.	Epidermal growth factor receptor pathway substrate 15.	0.995
ENSPREP00000015917	synrg	ENSPREP00000015917	ENSPREP00000013765	EH domain-containing protein.	Synergin, gamma.	0.995
LOC103464192	ENSPREP00000015917	ENSPREP00000029167	ENSPREP00000015917	Uncharacterized protein.	EH domain-containing protein.	0.995
LOC103464192	LOC103476383	ENSPREP00000029167	ENSPREP00000025820	Uncharacterized protein.	AP complex subunit beta.	0.710
LOC103464192	LOC103479233	ENSPREP00000029167	ENSPREP00000017318	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC103464192	ap2m1	ENSPREP00000029167	ENSPREP00000020784	Uncharacterized protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.846
LOC103464192	ap4b1	ENSPREP00000029167	ENSPREP00000008088	Uncharacterized protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.694
LOC103464192	eps15	ENSPREP00000029167	ENSPREP00000027199	Uncharacterized protein.	Epidermal growth factor receptor pathway substrate 15.	0.904
LOC103476383	ENSPREP00000015917	ENSPREP00000025820	ENSPREP00000015917	AP complex subunit beta.	EH domain-containing protein.	0.994
LOC103476383	LOC103464192	ENSPREP00000025820	ENSPREP00000029167	AP complex subunit beta.	Uncharacterized protein.	0.710
LOC103476383	LOC103479233	ENSPREP00000025820	ENSPREP00000017318	AP complex subunit beta.	Uncharacterized protein.	0.601
LOC103476383	LOC103479878	ENSPREP00000025820	ENSPREP00000018152	AP complex subunit beta.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.710