STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103461635Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (434 aa)    
Predicted Functional Partners:
ptch2
Patched 2.
   
 0.983
hhip
Hedgehog interacting protein.
    
 0.982
ptch1
Patched 1.
   
 0.981
cdon
Cell adhesion associated, oncogene regulated.
    
 0.924
boc
BOC cell adhesion associated, oncogene regulated.
    
 0.924
disp1
Dispatched homolog 1 (Drosophila).
   
 0.906
LOC103462620
Uncharacterized protein.
    
 0.831
disp2
Dispatched homolog 2 (Drosophila).
   
 0.820
Gas1
Growth arrest-specific 1a.
    
 0.809
ENSPREP00000030267
Growth arrest-specific 1b.
    
 0.809
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.