STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdc6Coiled-coil domain containing 6a. (520 aa)    
Predicted Functional Partners:
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.708
ppp4c
Serine/threonine-protein phosphatase.
    
 
 0.674
ppp2r1b
Protein phosphatase 2, regulatory subunit A, beta b.
    
 
 0.596
pdxdc1
Pyridoxal-dependent decarboxylase domain containing 1.
      
 0.540
LOC103460651
Cwf21 domain-containing protein.
      
 0.535
ppme1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
      
 0.532
Ppp4r1
Uncharacterized protein.
    
 
 0.473
ENSPREP00000016127
Uncharacterized protein.
    
 
 0.473
ENSPREP00000016150
Uncharacterized protein.
    
 
 0.473
JMJD8
Jumonji domain containing 8.
      
 0.440
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.