ENSPREP00000016198 protein (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

ENSPREP00000016198

Ig-like domain-containing protein. (117 aa)

Predicted Functional Partners:

ENSPREP00000002120

0.472

ENSPREP00000001052

0.471

uba52

0.466

ENSPREP00000002182

0.465

LOC103481840

0.461

cd79a

0.456

ENSPREP00000009389

0.452

ENSPREP00000016522

0.451

LOC103461875

0.450

ENSPREP00000002284

0.448

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001052	ENSPREP00000002182	ENSPREP00000001052	ENSPREP00000002182	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.402
ENSPREP00000001052	ENSPREP00000016198	ENSPREP00000001052	ENSPREP00000016198	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.471
ENSPREP00000002120	ENSPREP00000009389	ENSPREP00000002120	ENSPREP00000009389	IGv domain-containing protein.	Ig-like domain-containing protein.	0.432
ENSPREP00000002120	ENSPREP00000016198	ENSPREP00000002120	ENSPREP00000016198	IGv domain-containing protein.	Ig-like domain-containing protein.	0.472
ENSPREP00000002182	ENSPREP00000001052	ENSPREP00000002182	ENSPREP00000001052	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.402
ENSPREP00000002182	ENSPREP00000009389	ENSPREP00000002182	ENSPREP00000009389	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.453
ENSPREP00000002182	ENSPREP00000016198	ENSPREP00000002182	ENSPREP00000016198	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.465
ENSPREP00000002182	ENSPREP00000016522	ENSPREP00000002182	ENSPREP00000016522	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.492
ENSPREP00000002284	ENSPREP00000016198	ENSPREP00000002284	ENSPREP00000016198	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.448
ENSPREP00000002284	ENSPREP00000016522	ENSPREP00000002284	ENSPREP00000016522	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.446
ENSPREP00000009389	ENSPREP00000002120	ENSPREP00000009389	ENSPREP00000002120	Ig-like domain-containing protein.	IGv domain-containing protein.	0.432
ENSPREP00000009389	ENSPREP00000002182	ENSPREP00000009389	ENSPREP00000002182	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.453
ENSPREP00000009389	ENSPREP00000016198	ENSPREP00000009389	ENSPREP00000016198	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.452
ENSPREP00000009389	LOC103461875	ENSPREP00000009389	ENSPREP00000030497	Ig-like domain-containing protein.	Tissue factor pathway inhibitor.	0.450
ENSPREP00000009389	LOC103481840	ENSPREP00000009389	ENSPREP00000016438	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.461
ENSPREP00000009389	cd79a	ENSPREP00000009389	ENSPREP00000021581	Ig-like domain-containing protein.	CD79a molecule, immunoglobulin-associated alpha.	0.456
ENSPREP00000009389	uba52	ENSPREP00000009389	ENSPREP00000016516	Ig-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.466
ENSPREP00000016198	ENSPREP00000001052	ENSPREP00000016198	ENSPREP00000001052	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.471
ENSPREP00000016198	ENSPREP00000002120	ENSPREP00000016198	ENSPREP00000002120	Ig-like domain-containing protein.	IGv domain-containing protein.	0.472
ENSPREP00000016198	ENSPREP00000002182	ENSPREP00000016198	ENSPREP00000002182	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.465

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.878

expected number of edges:

10

PPI enrichment p-value:

1.46e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 102

1.46

2.9

1.80e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 56

1.72

4.42

2.05e-16

GO:0019843

rRNA binding

7 of 41

1.66

2.82

1.16e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 63

1.67

4.19

1.34e-16

GO:0044391

Ribosomal subunit

4 of 14

1.88

2.38

6.04e-06

GO:0015935

Small ribosomal subunit

2 of 6

1.95

1.21

0.0045

GO:0015934

Large ribosomal subunit

2 of 8

1.82

1.1

0.0065

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:139

Ribosome

11 of 51

1.76

4.68

8.93e-17

CL:144

Ribosome

9 of 39

1.79

4.27

1.24e-13

CL:145

rRNA-binding

6 of 31

1.71

2.8

4.47e-08

CL:196

Small ribosomal subunit, and Ribosome

3 of 5

2.2

2.11

7.99e-05

CL:231

Mixed, incl. Ribosomal L28 family, and Ribosomal protein L31

2 of 5

2.03

1.07

0.0093

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ppc03010

Ribosome

11 of 56

1.72

4.53

3.42e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 44

1.63

2.78

7.78e-09

GOCC:0043232

Intracellular non-membrane-bounded organelle

8 of 126

1.23

1.65

1.34e-07

GOCC:0043229

Intracellular organelle

11 of 281

1.02

1.3

1.86e-09

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 59

1.7

4.34

1.13e-16

KW-0699

rRNA-binding

7 of 39

1.68

3.01

2.78e-09

KW-0820

tRNA-binding

2 of 12

1.65

0.7

0.0425

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