STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (333 aa)    
Predicted Functional Partners:
tradd
Tnfrsf1a-associated via death domain.
    
 0.992
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
    
 0.987
sharpin
SHANK-associated RH domain interacting protein.
    
 0.979
tank
TRAF family member-associated NFKB activator.
   
 
 0.951
tnip1
TNFAIP3 interacting protein 1.
    
 
 0.948
rbck1
RanBP-type and C3HC4-type zinc finger containing 1.
    
 0.948
LOC103482437
Sharpin and rbck1 related.
    
 0.948
LOC103460775
Si:dkey-181m9.8.
    
 0.947
rnf31
Ring finger protein 31.
    
 0.947
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.939
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.