STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnfsf12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (231 aa)    
Predicted Functional Partners:
tnfsf13b
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.821
tnfsf11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
     
 0.755
LOC103471097
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
 0.707
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.701
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
   
  
 0.666
lig4
DNA ligase.
      
 0.659
LOC103471589
CD40 ligand; Belongs to the tumor necrosis factor family.
     
 0.629
tnfrsf11a
Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.
     
 0.607
LOC103462560
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
 
 0.588
ENSPREP00000029074
Tumor necrosis factor a (TNF superfamily, member 2).
     
 0.547
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.