STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plekhm1Pleckstrin homology domain containing, family M (with RUN domain) member 1. (1080 aa)    
Predicted Functional Partners:
map1lc3c
Microtubule-associated protein 1 light chain 3 gamma.
    
 
 0.859
vps39
VPS39 subunit of HOPS complex.
   
 
 0.650
uvrag
UV radiation resistance associated gene.
    
 
 0.594
vps11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.587
vps18
VPS18 core subunit of CORVET and HOPS complexes.
   
 
 0.577
snap29
Synaptosome associated protein 29.
      
 0.565
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.553
ostm1
Osteoclastogenesis associated transmembrane protein 1.
      
 0.549
stx17
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
      
 0.549
atg14
Autophagy related 14.
    
 
 0.489
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.