STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hltfHelicase-like transcription factor. (961 aa)    
Predicted Functional Partners:
rad18
RAD18 E3 ubiquitin protein ligase.
   
 0.980
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.974
ube2n
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.934
LOC103466094
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.934
rad51
RAD51 recombinase.
  
 
 0.904
LOC103472693
Protein S100; Belongs to the S-100 family.
   
 
 0.894
ENSPREP00000001588
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.873
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.873
LOC103465507
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.861
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.858
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.