node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPREP00000014189 | ENSPREP00000016750 | ENSPREP00000014189 | ENSPREP00000016750 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate-CoA ligase, ADP-forming, beta subunit. | 0.900 |
ENSPREP00000014189 | ENSPREP00000026406 | ENSPREP00000014189 | ENSPREP00000026406 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Oxoglutarate dehydrogenase. | 0.863 |
ENSPREP00000014189 | LOC103465156 | ENSPREP00000014189 | ENSPREP00000007459 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.578 |
ENSPREP00000014189 | LOC103479501 | ENSPREP00000014189 | ENSPREP00000000828 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate dehydrogenase complex, subunit C, integral membrane protein. | 0.528 |
ENSPREP00000014189 | SDHB | ENSPREP00000014189 | ENSPREP00000014377 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.578 |
ENSPREP00000014189 | cs | ENSPREP00000014189 | ENSPREP00000033337 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Citrate synthase; Belongs to the citrate synthase family. | 0.956 |
ENSPREP00000014189 | dld | ENSPREP00000014189 | ENSPREP00000003162 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoyl dehydrogenase. | 0.999 |
ENSPREP00000014189 | ogdh | ENSPREP00000014189 | ENSPREP00000022672 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). | 0.863 |
ENSPREP00000014189 | sdha | ENSPREP00000014189 | ENSPREP00000020514 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.734 |
ENSPREP00000014189 | suclg1 | ENSPREP00000014189 | ENSPREP00000013705 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.786 |
ENSPREP00000016750 | ENSPREP00000014189 | ENSPREP00000016750 | ENSPREP00000014189 | Succinate-CoA ligase, ADP-forming, beta subunit. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.900 |
ENSPREP00000016750 | ENSPREP00000026406 | ENSPREP00000016750 | ENSPREP00000026406 | Succinate-CoA ligase, ADP-forming, beta subunit. | Oxoglutarate dehydrogenase. | 0.927 |
ENSPREP00000016750 | LOC103465156 | ENSPREP00000016750 | ENSPREP00000007459 | Succinate-CoA ligase, ADP-forming, beta subunit. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.949 |
ENSPREP00000016750 | LOC103479501 | ENSPREP00000016750 | ENSPREP00000000828 | Succinate-CoA ligase, ADP-forming, beta subunit. | Succinate dehydrogenase complex, subunit C, integral membrane protein. | 0.874 |
ENSPREP00000016750 | SDHB | ENSPREP00000016750 | ENSPREP00000014377 | Succinate-CoA ligase, ADP-forming, beta subunit. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.949 |
ENSPREP00000016750 | cs | ENSPREP00000016750 | ENSPREP00000033337 | Succinate-CoA ligase, ADP-forming, beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.966 |
ENSPREP00000016750 | dld | ENSPREP00000016750 | ENSPREP00000003162 | Succinate-CoA ligase, ADP-forming, beta subunit. | Dihydrolipoyl dehydrogenase. | 0.972 |
ENSPREP00000016750 | ogdh | ENSPREP00000016750 | ENSPREP00000022672 | Succinate-CoA ligase, ADP-forming, beta subunit. | Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). | 0.927 |
ENSPREP00000016750 | sdha | ENSPREP00000016750 | ENSPREP00000020514 | Succinate-CoA ligase, ADP-forming, beta subunit. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.974 |
ENSPREP00000016750 | suclg1 | ENSPREP00000016750 | ENSPREP00000013705 | Succinate-CoA ligase, ADP-forming, beta subunit. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.999 |