STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)    
Predicted Functional Partners:
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.996
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.993
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.986
ENSPREP00000032744
Retinoblastoma 1.
   
 0.986
e2f1
E2F transcription factor 1.
   
 0.983
LOC103465183
Cyclin-dependent kinase inhibitor 1A.
    
 0.973
LOC103465909
Cyclin-dependent kinase inhibitor 1Bb.
    
 0.973
LOC103465931
Cyclin-dependent kinase inhibitor 1Cb.
    
 0.973
ENSPREP00000013852
Uncharacterized protein.
    
 0.971
e2f2
Si:ch211-160f23.5.
   
 0.965
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (16%) [HD]