STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
 0.907
LOC103470494
Uncharacterized protein.
   
 0.907
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.787
LOC103468963
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.787
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.787
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.787
LOC103481373
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.787
ppp2ca
Serine/threonine-protein phosphatase.
   
 0.717
LOC103471193
Serine/threonine-protein phosphatase.
   
 0.717
LOC103459892
Calcium/calmodulin-dependent protein kinase II alpha.
    
  0.691
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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