STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103468291Cyclin-dependent kinase 5 activator. (334 aa)    
Predicted Functional Partners:
cdk5
Cyclin-dependent kinase 5.
    
 0.928
met
MET proto-oncogene, receptor tyrosine kinase.
   
  0.509
LOC103464537
Macrophage stimulating 1 receptor a.
   
  0.509
mst1r
Macrophage stimulating 1 receptor b.
   
  0.509
nrp1
Neuropilin; Belongs to the neuropilin family.
   
 
  0.457
ENSPREP00000023272
Uncharacterized protein.
  
  
 
0.418
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
  0.411
LOC103472964
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
  0.411
gsk3a
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
  0.411
tp73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
     
 0.403
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.