nsd3 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nsd3

Nuclear receptor binding SET domain protein 3. (1621 aa)

Predicted Functional Partners:

plod1

0.684

plod2

0.684

setd3

0.655

ash2l

0.655

rbbp5

0.653

eed

0.645

setd7

0.629

mre11

0.601

bard1

0.586

uba52

0.567

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ash2l	nsd3	ENSPREP00000022292	ENSPREP00000017535	Ash2 like, histone lysine methyltransferase complex subunit.	Nuclear receptor binding SET domain protein 3.	0.655
ash2l	rbbp5	ENSPREP00000022292	ENSPREP00000014432	Ash2 like, histone lysine methyltransferase complex subunit.	Retinoblastoma binding protein 5.	0.999
ash2l	setd3	ENSPREP00000022292	ENSPREP00000017405	Ash2 like, histone lysine methyltransferase complex subunit.	Protein-histidine N-methyltransferase.	0.557
ash2l	setd7	ENSPREP00000022292	ENSPREP00000001051	Ash2 like, histone lysine methyltransferase complex subunit.	SET domain containing 7, histone lysine methyltransferase.	0.698
ash2l	uba52	ENSPREP00000022292	ENSPREP00000016516	Ash2 like, histone lysine methyltransferase complex subunit.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.888
bard1	mre11	ENSPREP00000017694	ENSPREP00000033509	BRCA1 associated RING domain 1.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.986
bard1	nsd3	ENSPREP00000017694	ENSPREP00000017535	BRCA1 associated RING domain 1.	Nuclear receptor binding SET domain protein 3.	0.586
bard1	setd7	ENSPREP00000017694	ENSPREP00000001051	BRCA1 associated RING domain 1.	SET domain containing 7, histone lysine methyltransferase.	0.432
bard1	uba52	ENSPREP00000017694	ENSPREP00000016516	BRCA1 associated RING domain 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.940
eed	nsd3	ENSPREP00000023484	ENSPREP00000017535	Embryonic ectoderm development.	Nuclear receptor binding SET domain protein 3.	0.645
eed	setd7	ENSPREP00000023484	ENSPREP00000001051	Embryonic ectoderm development.	SET domain containing 7, histone lysine methyltransferase.	0.936
eed	uba52	ENSPREP00000023484	ENSPREP00000016516	Embryonic ectoderm development.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.559
mre11	bard1	ENSPREP00000033509	ENSPREP00000017694	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	BRCA1 associated RING domain 1.	0.986
mre11	nsd3	ENSPREP00000033509	ENSPREP00000017535	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Nuclear receptor binding SET domain protein 3.	0.601
mre11	uba52	ENSPREP00000033509	ENSPREP00000016516	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.529
nsd3	ash2l	ENSPREP00000017535	ENSPREP00000022292	Nuclear receptor binding SET domain protein 3.	Ash2 like, histone lysine methyltransferase complex subunit.	0.655
nsd3	bard1	ENSPREP00000017535	ENSPREP00000017694	Nuclear receptor binding SET domain protein 3.	BRCA1 associated RING domain 1.	0.586
nsd3	eed	ENSPREP00000017535	ENSPREP00000023484	Nuclear receptor binding SET domain protein 3.	Embryonic ectoderm development.	0.645
nsd3	mre11	ENSPREP00000017535	ENSPREP00000033509	Nuclear receptor binding SET domain protein 3.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.601
nsd3	plod1	ENSPREP00000017535	ENSPREP00000013032	Nuclear receptor binding SET domain protein 3.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.	0.684