STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103458422TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (289 aa)    
Predicted Functional Partners:
LOC103469561
Uncharacterized protein.
    
 0.994
LOC103473338
Tumor necrosis factor receptor superfamily, member a.
    
 0.983
ENSPREP00000002275
DED domain-containing protein.
    
 0.951
LOC103456720
TNF superfamily member 10; Belongs to the tumor necrosis factor family.
  
  
 
0.903
cflar
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.834
LOC103478931
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.815
LOC103459939
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.815
ENSPREP00000020797
TNFR-Cys domain-containing protein.
     
 0.801
LOC103479635
Death domain-containing protein.
    
 0.767
ENSPREP00000002926
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
     
 0.746
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.