LOC103473119 protein (Poecilia reticulata) - STRING interaction network

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LOC103473119

3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (577 aa)

Predicted Functional Partners:

hmgcr

0.999

LOC103473284

0.999

acat2

0.996

acat1

0.993

acaa2

0.992

hmgcl

0.991

acaa1

0.991

hmgcll1

0.991

sqle

0.977

fdps

0.968

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103473119	LOC103473284	ENSPREP00000017837	ENSPREP00000027438	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.999
LOC103473119	acaa1	ENSPREP00000017837	ENSPREP00000006361	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
LOC103473119	acaa2	ENSPREP00000017837	ENSPREP00000016912	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.992
LOC103473119	acat1	ENSPREP00000017837	ENSPREP00000015486	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.993
LOC103473119	acat2	ENSPREP00000017837	ENSPREP00000008323	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
LOC103473119	fdps	ENSPREP00000017837	ENSPREP00000026097	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.968
LOC103473119	hmgcl	ENSPREP00000017837	ENSPREP00000001998	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.991
LOC103473119	hmgcll1	ENSPREP00000017837	ENSPREP00000032813	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.991
LOC103473119	hmgcr	ENSPREP00000017837	ENSPREP00000018171	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.999
LOC103473119	sqle	ENSPREP00000017837	ENSPREP00000024231	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Squalene epoxidase a.	0.977
LOC103473284	LOC103473119	ENSPREP00000027438	ENSPREP00000017837	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.999
LOC103473284	acat1	ENSPREP00000027438	ENSPREP00000015486	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.414
LOC103473284	acat2	ENSPREP00000027438	ENSPREP00000008323	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.414
LOC103473284	fdps	ENSPREP00000027438	ENSPREP00000026097	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.636
LOC103473284	hmgcl	ENSPREP00000027438	ENSPREP00000001998	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.791
LOC103473284	hmgcll1	ENSPREP00000027438	ENSPREP00000032813	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.765
LOC103473284	hmgcr	ENSPREP00000027438	ENSPREP00000018171	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.901
LOC103473284	sqle	ENSPREP00000027438	ENSPREP00000024231	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Squalene epoxidase a.	0.859
acaa1	LOC103473119	ENSPREP00000006361	ENSPREP00000017837	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.991
acaa1	acaa2	ENSPREP00000006361	ENSPREP00000016912	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.920

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