node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103472230 | dicer1 | ENSPREP00000002849 | ENSPREP00000017960 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. | 0.903 |
LOC103472230 | prkra | ENSPREP00000002849 | ENSPREP00000008305 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein kinase, interferon-inducible double stranded RNA dependent activator. | 0.749 |
LOC103472230 | stau1 | ENSPREP00000002849 | ENSPREP00000004951 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staufen double-stranded RNA binding protein 1. | 0.667 |
LOC103472230 | stau2 | ENSPREP00000002849 | ENSPREP00000026316 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staufen double-stranded RNA binding protein 2. | 0.667 |
LOC103472230 | tarbp2 | ENSPREP00000002849 | ENSPREP00000011475 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.749 |
LOC103473053 | dicer1 | ENSPREP00000013374 | ENSPREP00000017960 | Uncharacterized protein; Belongs to the argonaute family. | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. | 0.903 |
LOC103473053 | prkra | ENSPREP00000013374 | ENSPREP00000008305 | Uncharacterized protein; Belongs to the argonaute family. | Protein kinase, interferon-inducible double stranded RNA dependent activator. | 0.749 |
LOC103473053 | stau1 | ENSPREP00000013374 | ENSPREP00000004951 | Uncharacterized protein; Belongs to the argonaute family. | Staufen double-stranded RNA binding protein 1. | 0.667 |
LOC103473053 | stau2 | ENSPREP00000013374 | ENSPREP00000026316 | Uncharacterized protein; Belongs to the argonaute family. | Staufen double-stranded RNA binding protein 2. | 0.667 |
LOC103473053 | tarbp2 | ENSPREP00000013374 | ENSPREP00000011475 | Uncharacterized protein; Belongs to the argonaute family. | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.749 |
LOC103477771 | dicer1 | ENSPREP00000009729 | ENSPREP00000017960 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. | 0.903 |
LOC103477771 | prkra | ENSPREP00000009729 | ENSPREP00000008305 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Protein kinase, interferon-inducible double stranded RNA dependent activator. | 0.749 |
LOC103477771 | stau1 | ENSPREP00000009729 | ENSPREP00000004951 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Staufen double-stranded RNA binding protein 1. | 0.667 |
LOC103477771 | stau2 | ENSPREP00000009729 | ENSPREP00000026316 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Staufen double-stranded RNA binding protein 2. | 0.667 |
LOC103477771 | tarbp2 | ENSPREP00000009729 | ENSPREP00000011475 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.833 |
LOC103477773 | dicer1 | ENSPREP00000009674 | ENSPREP00000017960 | Argonaute RISC component 1; Belongs to the argonaute family. | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. | 0.903 |
LOC103477773 | prkra | ENSPREP00000009674 | ENSPREP00000008305 | Argonaute RISC component 1; Belongs to the argonaute family. | Protein kinase, interferon-inducible double stranded RNA dependent activator. | 0.749 |
LOC103477773 | stau1 | ENSPREP00000009674 | ENSPREP00000004951 | Argonaute RISC component 1; Belongs to the argonaute family. | Staufen double-stranded RNA binding protein 1. | 0.667 |
LOC103477773 | stau2 | ENSPREP00000009674 | ENSPREP00000026316 | Argonaute RISC component 1; Belongs to the argonaute family. | Staufen double-stranded RNA binding protein 2. | 0.667 |
LOC103477773 | tarbp2 | ENSPREP00000009674 | ENSPREP00000011475 | Argonaute RISC component 1; Belongs to the argonaute family. | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.749 |