STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103480481Zgc:114045. (492 aa)    
Predicted Functional Partners:
ENSPREP00000015831
Uncharacterized protein.
    
 0.951
ENSPREP00000015870
Uncharacterized protein.
    
 0.951
ENSPREP00000015917
EH domain-containing protein.
    
 0.951
itsn2
Intersectin 2a.
    
 0.951
vamp7
Synaptobrevin-like 1; Belongs to the synaptobrevin family.
    
 0.717
ENSPREP00000007450
Uncharacterized protein.
    
 0.654
ENSPREP00000008107
Intersectin 1 (SH3 domain protein).
    
 0.654
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.512
LOC103468143
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
     
 0.462
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
     
 0.447
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.