STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prex1Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1503 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.737
LOC103465423
Cell division cycle 42.
    
 0.737
dock4
Dedicator of cytokinesis 4b; Belongs to the DOCK family.
   
 0.669
LOC103472837
Uncharacterized protein.
    
 0.623
LOC103477993
Uncharacterized protein.
    
 0.623
LOC103477991
Uncharacterized protein.
    
 0.623
RHOG
Ras homolog family member G.
    
 0.578
ENSPREP00000010679
Ras homolog gene family, member Gd.
    
 0.578
LOC103471173
Uncharacterized protein.
    
 0.578
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.575
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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