esam protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

esam

Endothelial cell adhesion molecule a. (449 aa)

Predicted Functional Partners:

LOC103474209

0.901

Cldn5

0.712

LOC103473180

0.712

LOC103473229

0.614

LOC103476642

0.563

ENSPREP00000004666

0.492

tsta3

0.434

egfl7

0.431

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cldn5	LOC103473180	ENSPREP00000017247	ENSPREP00000020548	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
Cldn5	LOC103473229	ENSPREP00000017247	ENSPREP00000024159	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Occludin a.	0.534
Cldn5	LOC103474209	ENSPREP00000017247	ENSPREP00000016668	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Endothelial cell adhesion molecule b.	0.460
Cldn5	LOC103476642	ENSPREP00000017247	ENSPREP00000010042	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.678
Cldn5	egfl7	ENSPREP00000017247	ENSPREP00000031151	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	EGF-like-domain, multiple 7.	0.427
Cldn5	esam	ENSPREP00000017247	ENSPREP00000018256	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Endothelial cell adhesion molecule a.	0.712
ENSPREP00000004666	LOC103476642	ENSPREP00000004666	ENSPREP00000010042	Si:dkey-237i9.8.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.695
ENSPREP00000004666	esam	ENSPREP00000004666	ENSPREP00000018256	Si:dkey-237i9.8.	Endothelial cell adhesion molecule a.	0.492
LOC103473180	Cldn5	ENSPREP00000020548	ENSPREP00000017247	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
LOC103473180	LOC103473229	ENSPREP00000020548	ENSPREP00000024159	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Occludin a.	0.534
LOC103473180	LOC103474209	ENSPREP00000020548	ENSPREP00000016668	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Endothelial cell adhesion molecule b.	0.460
LOC103473180	LOC103476642	ENSPREP00000020548	ENSPREP00000010042	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.678
LOC103473180	egfl7	ENSPREP00000020548	ENSPREP00000031151	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	EGF-like-domain, multiple 7.	0.427
LOC103473180	esam	ENSPREP00000020548	ENSPREP00000018256	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Endothelial cell adhesion molecule a.	0.712
LOC103473229	Cldn5	ENSPREP00000024159	ENSPREP00000017247	Occludin a.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.534
LOC103473229	LOC103473180	ENSPREP00000024159	ENSPREP00000020548	Occludin a.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.534
LOC103473229	LOC103476642	ENSPREP00000024159	ENSPREP00000010042	Occludin a.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.642
LOC103473229	esam	ENSPREP00000024159	ENSPREP00000018256	Occludin a.	Endothelial cell adhesion molecule a.	0.614
LOC103474209	Cldn5	ENSPREP00000016668	ENSPREP00000017247	Endothelial cell adhesion molecule b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.460
LOC103474209	LOC103473180	ENSPREP00000016668	ENSPREP00000020548	Endothelial cell adhesion molecule b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.460