STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000018284Sortilin-Vps10 domain-containing protein. (374 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
     
 0.942
SORCS1
Sortilin related VPS10 domain containing receptor 1.
 
      0.899
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
     
 0.593
igf2r
Insulin-like growth factor 2 receptor.
    
 0.516
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.513
psma1
Proteasome endopeptidase complex.
    
   0.441
LOC103479568
Proteasome subunit alpha type.
    
   0.441
psma4
Proteasome subunit alpha type.
    
   0.441
psmb1
Proteasome subunit beta.
    
   0.441
LOC103474743
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.434
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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