STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000018760Protein kinase domain-containing protein. (507 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.996
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.984
irak4
Interleukin-1 receptor-associated kinase 4.
   
0.977
tollip
Toll interacting protein.
   
 0.946
ENSPREP00000007989
RanBP2-type domain-containing protein.
    
 0.853
Tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.853
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.813
LOC103480122
Pellino E3 ubiquitin protein ligase family member 3.
    
 0.799
LOC103459010
Pellino E3 ubiquitin protein ligase family member 2.
    
 0.799
LOC103457902
Uncharacterized protein.
    
 0.799
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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