STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brafB-Raf proto-oncogene, serine/threonine kinase. (781 aa)    
Predicted Functional Partners:
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.982
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.979
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.979
LOC103469088
Zgc:55558.
   
 0.976
hras
HRas proto-oncogene, GTPase a.
   
 0.976
LOC103467749
Uncharacterized protein.
   
 0.974
rap1b
Uncharacterized protein.
   
 0.974
LOC103464617
RAP1A, member of RAS oncogene family b.
   
 0.974
rras2
RAS related 2.
   
 0.963
mras
Muscle RAS oncogene homolog.
   
 0.962
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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