tbkbp1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tbkbp1

TBK1 binding protein 1. (699 aa)

Predicted Functional Partners:

tank

0.925

ENSPREP00000005404

0.862

tbk1

0.862

azi2

0.854

Calcoco2

0.789

ikbkb

0.604

CHUK

0.604

LOC103476976

0.604

rb1cc1

0.459

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	LOC103476976	ENSPREP00000020163	ENSPREP00000032137	Component of inhibitor of nuclear factor kappa B kinase complex.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.943
CHUK	azi2	ENSPREP00000020163	ENSPREP00000017750	Component of inhibitor of nuclear factor kappa B kinase complex.	5-azacytidine induced 2.	0.583
CHUK	ikbkb	ENSPREP00000020163	ENSPREP00000016563	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.950
CHUK	tank	ENSPREP00000020163	ENSPREP00000011950	Component of inhibitor of nuclear factor kappa B kinase complex.	TRAF family member-associated NFKB activator.	0.530
CHUK	tbkbp1	ENSPREP00000020163	ENSPREP00000018982	Component of inhibitor of nuclear factor kappa B kinase complex.	TBK1 binding protein 1.	0.604
Calcoco2	ENSPREP00000005404	ENSPREP00000019405	ENSPREP00000005404	SKICH domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.661
Calcoco2	azi2	ENSPREP00000019405	ENSPREP00000017750	SKICH domain-containing protein.	5-azacytidine induced 2.	0.905
Calcoco2	rb1cc1	ENSPREP00000019405	ENSPREP00000012221	SKICH domain-containing protein.	RB1-inducible coiled-coil 1.	0.952
Calcoco2	tbk1	ENSPREP00000019405	ENSPREP00000027853	SKICH domain-containing protein.	TANK-binding kinase 1.	0.964
Calcoco2	tbkbp1	ENSPREP00000019405	ENSPREP00000018982	SKICH domain-containing protein.	TBK1 binding protein 1.	0.789
ENSPREP00000005404	Calcoco2	ENSPREP00000005404	ENSPREP00000019405	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	SKICH domain-containing protein.	0.661
ENSPREP00000005404	LOC103476976	ENSPREP00000005404	ENSPREP00000032137	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.401
ENSPREP00000005404	azi2	ENSPREP00000005404	ENSPREP00000017750	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	5-azacytidine induced 2.	0.855
ENSPREP00000005404	tank	ENSPREP00000005404	ENSPREP00000011950	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TRAF family member-associated NFKB activator.	0.948
ENSPREP00000005404	tbkbp1	ENSPREP00000005404	ENSPREP00000018982	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	TBK1 binding protein 1.	0.862
LOC103476976	CHUK	ENSPREP00000032137	ENSPREP00000020163	Component of inhibitor of nuclear factor kappa B kinase complex.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.943
LOC103476976	ENSPREP00000005404	ENSPREP00000032137	ENSPREP00000005404	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.401
LOC103476976	azi2	ENSPREP00000032137	ENSPREP00000017750	Component of inhibitor of nuclear factor kappa B kinase complex.	5-azacytidine induced 2.	0.583
LOC103476976	ikbkb	ENSPREP00000032137	ENSPREP00000016563	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.903
LOC103476976	tank	ENSPREP00000032137	ENSPREP00000011950	Component of inhibitor of nuclear factor kappa B kinase complex.	TRAF family member-associated NFKB activator.	0.499