STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAALADL2N-acetylated alpha-linked acidic dipeptidase like 2. (783 aa)    
Predicted Functional Partners:
epor
Erythropoietin receptor.
    
 0.604
tmem117
Transmembrane protein 117.
      
 0.549
dock4
Dedicator of cytokinesis 4b; Belongs to the DOCK family.
     
 0.500
Katnal2
Katanin p60 subunit A-like 2.
   
 
 0.482
snap29
Synaptosome associated protein 29.
     
 0.476
LOC103464606
Kelch repeat and BTB (POZ) domain containing 12.
     
 0.472
tmem161b
Transmembrane protein 161B.
      
 0.470
sorl1
Sortilin-related receptor, L(DLR class) A repeats containing.
     
 0.466
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.461
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
     
 0.456
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.