STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103457124Serine peptidase inhibitor, Kunitz type 1 b. (500 aa)    
Predicted Functional Partners:
HGFAC
HGF activator.
    
 0.841
ENSPREP00000003194
Kringle domain-containing protein.
    
 0.621
mst1l
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.621
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.621
hpn
Hepsin; Belongs to the peptidase S1 family.
    
 0.532
LOC103460238
Uncharacterized protein.
   
 0.465
LOC103475070
Suppression of tumorigenicity 14a.
   
 0.465
podxl2
Uncharacterized protein.
   
 
 0.414
naglu
N-acetylglucosaminidase, alpha.
   
  
 0.409
tsr1
TSR1 ribosome maturation factor.
   
  
 0.409
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.