STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103481734Fibrosin. (1128 aa)    
Predicted Functional Partners:
pcgf5
Polycomb group ring finger 5a.
    
 0.887
chek2
Checkpoint kinase 2.
   
 0.838
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.812
PCGF3
Polycomb group ring finger 3.
    
 0.753
PLK1
Serine/threonine-protein kinase PLK.
   
 0.645
plk3
Serine/threonine-protein kinase PLK.
   
 0.645
plk4
Polo-like kinase 4 (Drosophila).
   
 0.645
plk2
Serine/threonine-protein kinase PLK.
   
 0.645
ccne1
Cyclin E1; Belongs to the cyclin family.
   
 0.633
ccne2
Cyclin E2; Belongs to the cyclin family.
   
 0.633
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.