STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gclmGlutamate-cysteine ligase, modifier subunit. (281 aa)    
Predicted Functional Partners:
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 0.996
gss
Glutathione synthetase.
   
 0.869
nfe2l2
Nuclear factor, erythroid 2-like 2a.
     
 0.603
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
  
 
 0.589
srxn1
Sulfiredoxin.
   
  
 0.586
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.577
Suox
Sulfite oxidase.
      
 0.549
GPX2
Glutathione peroxidase 2.
  
  
 0.501
LOC103465416
Thioredoxin reductase 3.
   
 
 0.443
Sod3
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
  
 0.442
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.