STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
insrInsulin receptor a. (1178 aa)    
Predicted Functional Partners:
igf1
Insulin-like growth factor 1.
    
 0.818
igf2
IlGF domain-containing protein.
    
 0.793
LOC103476384
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.766
ENSPREP00000030771
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.766
irs2
Insulin receptor substrate 2b.
   
 0.757
LOC103476518
Insulin receptor substrate 2a.
   
 0.707
LOC103467754
Tyrosine-protein phosphatase non-receptor type.
   
 0.705
LOC103480255
Insulin receptor substrate 4a.
   
 0.705
LOC103472442
Tyrosine-protein phosphatase non-receptor type.
   
 0.705
ptpn2
Tyrosine-protein phosphatase non-receptor type.
   
 0.705
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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