STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103474271Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2002 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.989
LOC103474422
Sodium channel, voltage-gated, type II, beta.
   
 0.791
scn1b
Sodium channel, voltage-gated, type I, beta b.
   
 0.689
ENSPREP00000024427
IGv domain-containing protein.
   
 0.689
wdr35
WD repeat-containing protein 35.
    
 0.661
slc39a14
Solute carrier family 39 member 14.
   
  
 0.651
IFT122
Intraflagellar transport 122.
   
 0.651
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
    
 0.636
wdr19
WD repeat domain 19.
    
 0.630
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 0.592
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]