STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (294 aa)    
Predicted Functional Partners:
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.770
LOC103476312
Uncharacterized protein.
    
 0.770
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.770
spry1
Sprouty homolog 1, antagonist of FGF signaling (Drosophila).
  
0.570
ENSPREP00000009325
GRB2 related adaptor protein b.
    
 0.565
ENSPREP00000009358
Uncharacterized protein.
    
 0.565
grap2
GRB2 related adaptor protein 2a.
    
 0.565
grb2
Growth factor receptor-bound protein 2b.
    
 0.565
LOC103469145
GRB2 related adaptor protein a.
    
 0.565
LOC103471128
Heparin-binding EGF-like growth factor a.
   
 
 0.530
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.