LOC103464167 protein (Poecilia reticulata) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Score

LOC103464167

Vitellogenin 3, phosvitinless. (1264 aa)

Predicted Functional Partners:

ENSPREP00000015831

0.943

ENSPREP00000015870

0.943

ENSPREP00000015917

0.943

itsn2

0.943

esr1

0.863

LOC103473017

0.827

mttp

0.807

LOC103477848

0.748

LOC103477850

0.716

LOC103477849

0.716

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000015831	ENSPREP00000015870	ENSPREP00000015831	ENSPREP00000015870	Uncharacterized protein.	Uncharacterized protein.	0.995
ENSPREP00000015831	ENSPREP00000015917	ENSPREP00000015831	ENSPREP00000015917	Uncharacterized protein.	EH domain-containing protein.	0.952
ENSPREP00000015831	LOC103464167	ENSPREP00000015831	ENSPREP00000020196	Uncharacterized protein.	Vitellogenin 3, phosvitinless.	0.943
ENSPREP00000015831	itsn2	ENSPREP00000015831	ENSPREP00000017512	Uncharacterized protein.	Intersectin 2a.	0.953
ENSPREP00000015870	ENSPREP00000015831	ENSPREP00000015870	ENSPREP00000015831	Uncharacterized protein.	Uncharacterized protein.	0.995
ENSPREP00000015870	ENSPREP00000015917	ENSPREP00000015870	ENSPREP00000015917	Uncharacterized protein.	EH domain-containing protein.	0.952
ENSPREP00000015870	LOC103464167	ENSPREP00000015870	ENSPREP00000020196	Uncharacterized protein.	Vitellogenin 3, phosvitinless.	0.943
ENSPREP00000015870	itsn2	ENSPREP00000015870	ENSPREP00000017512	Uncharacterized protein.	Intersectin 2a.	0.952
ENSPREP00000015917	ENSPREP00000015831	ENSPREP00000015917	ENSPREP00000015831	EH domain-containing protein.	Uncharacterized protein.	0.952
ENSPREP00000015917	ENSPREP00000015870	ENSPREP00000015917	ENSPREP00000015870	EH domain-containing protein.	Uncharacterized protein.	0.952
ENSPREP00000015917	LOC103464167	ENSPREP00000015917	ENSPREP00000020196	EH domain-containing protein.	Vitellogenin 3, phosvitinless.	0.943
ENSPREP00000015917	itsn2	ENSPREP00000015917	ENSPREP00000017512	EH domain-containing protein.	Intersectin 2a.	0.952
LOC103464167	ENSPREP00000015831	ENSPREP00000020196	ENSPREP00000015831	Vitellogenin 3, phosvitinless.	Uncharacterized protein.	0.943
LOC103464167	ENSPREP00000015870	ENSPREP00000020196	ENSPREP00000015870	Vitellogenin 3, phosvitinless.	Uncharacterized protein.	0.943
LOC103464167	ENSPREP00000015917	ENSPREP00000020196	ENSPREP00000015917	Vitellogenin 3, phosvitinless.	EH domain-containing protein.	0.943
LOC103464167	LOC103473017	ENSPREP00000020196	ENSPREP00000013094	Vitellogenin 3, phosvitinless.	Apolipoprotein Ea.	0.827
LOC103464167	LOC103477848	ENSPREP00000020196	ENSPREP00000006664	Vitellogenin 3, phosvitinless.	Apolipoprotein Eb.	0.748
LOC103464167	LOC103477849	ENSPREP00000020196	ENSPREP00000006633	Vitellogenin 3, phosvitinless.	Uncharacterized protein.	0.716
LOC103464167	LOC103477850	ENSPREP00000020196	ENSPREP00000006628	Vitellogenin 3, phosvitinless.	Uncharacterized protein.	0.716
LOC103464167	esr1	ENSPREP00000020196	ENSPREP00000006015	Vitellogenin 3, phosvitinless.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.863

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Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.927

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 349

1.77

4.26

7.07e-14

GO:0002181

Cytoplasmic translation

3 of 47

2.12

1.61

0.00077

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 165

2.05

5.56

1.01e-14

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 192

2.03

6.14

3.18e-17

GO:0022626

Cytosolic ribosome

5 of 56

2.27

3.69

3.28e-08

GO:0022625

Cytosolic large ribosomal subunit

4 of 34

2.39

3.12

8.90e-07

GO:0044391

Ribosomal subunit

5 of 143

1.86

2.57

1.50e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:360

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

9 of 64

2.47

8.07

5.64e-18

CL:368

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

8 of 54

2.49

7.58

1.36e-16

CL:370

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

7 of 43

2.53

6.85

1.20e-14

CL:295

Formation of a pool of free 40S subunits, and Delayed rectifier potassium channel activity

10 of 190

2.04

6.2

2.28e-17

CL:372

Cytosolic large ribosomal subunit, and Ribosomal protein L13

4 of 18

2.66

3.88

4.79e-08

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pret03010

Ribosome

10 of 113

2.26

8.1

2.54e-20

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

9 of 107

2.24

6.81

1.47e-16

MAP-72689

Formation of a pool of free 40S subunits

9 of 112

2.22

6.74

1.47e-16

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

9 of 119

2.2

6.64

1.47e-16

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

9 of 121

2.19

6.61

1.47e-16

MAP-156827

L13a-mediated translational silencing of Ceruloplasmin expression

9 of 129

2.16

6.51

1.48e-16

(more ...)

Tissue Expression (TISSUES)

tissue

description

count in network

strength

signal

false discovery rate

BTO:0001489

Whole body

11 of 13032

0.24

0.23

0.0187

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0022626

Cytosolic ribosome

9 of 55

2.53

8.69

4.91e-19

GOCC:0015934

Large ribosomal subunit

7 of 66

2.34

5.88

3.14e-13

GOCC:0044391

Ribosomal subunit

8 of 121

2.14

5.59

6.83e-14

GOCC:0022625

Cytosolic large ribosomal subunit

5 of 16

2.81

5.48

4.59e-11

GOCC:0042788

Polysomal ribosome

4 of 21

2.6

3.77

6.98e-08

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

4 of 59

2.15

2.61

5.68e-06

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