STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pax6Paired box 6b. (431 aa)    
Predicted Functional Partners:
hras
HRas proto-oncogene, GTPase a.
   
 
 0.782
TIMM22
Translocase of inner mitochondrial membrane 22.
    
 0.746
LOC103481539
SIX homeobox 3b.
   
 
 0.677
Six3
SIX homeobox 3a.
   
 
 0.676
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.649
timm10
Translocase of inner mitochondrial membrane 10 homolog (yeast).
   
 0.640
timm9
Translocase of inner mitochondrial membrane 9 homolog.
   
 
 0.634
oca2
Oculocutaneous albinism II.
      
 0.626
vax1
Ventral anterior homeobox 1.
    
 
 0.623
rom1
Retinal outer segment membrane protein 1b.
      
 0.597
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.