LOC103471969 protein (Poecilia reticulata) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

LOC103471969

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a. (230 aa)

Predicted Functional Partners:

LOC103468460

0.818

LOC103482005

0.818

LOC103464091

0.801

crebbp

0.801

tfap2d

0.604

tfap2e

0.493

tfap2b

0.493

tfap2c

0.493

tfap2a

0.493

nrg4

0.440

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	LOC103468460	ENSPREP00000000408	ENSPREP00000026558	CREB binding protein a.	E1A binding protein p300 b.	0.928
LOC103464091	LOC103471969	ENSPREP00000000408	ENSPREP00000020490	CREB binding protein a.	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.	0.801
LOC103464091	LOC103482005	ENSPREP00000000408	ENSPREP00000030842	CREB binding protein a.	E1A binding protein p300 a.	0.928
LOC103464091	tfap2a	ENSPREP00000000408	ENSPREP00000025513	CREB binding protein a.	Transcription factor AP-2 alpha.	0.418
LOC103464091	tfap2b	ENSPREP00000000408	ENSPREP00000023481	CREB binding protein a.	Transcription factor AP-2 beta.	0.418
LOC103464091	tfap2c	ENSPREP00000000408	ENSPREP00000023993	CREB binding protein a.	Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma).	0.418
LOC103464091	tfap2d	ENSPREP00000000408	ENSPREP00000023456	CREB binding protein a.	Transcription factor AP-2 delta (activating enhancer binding protein 2 delta).	0.544
LOC103464091	tfap2e	ENSPREP00000000408	ENSPREP00000015078	CREB binding protein a.	Transcription factor AP-2 epsilon.	0.418
LOC103468460	LOC103464091	ENSPREP00000026558	ENSPREP00000000408	E1A binding protein p300 b.	CREB binding protein a.	0.928
LOC103468460	LOC103471969	ENSPREP00000026558	ENSPREP00000020490	E1A binding protein p300 b.	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.	0.818
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	crebbp	ENSPREP00000026558	ENSPREP00000011232	E1A binding protein p300 b.	CREB binding protein b.	0.992
LOC103468460	tfap2a	ENSPREP00000026558	ENSPREP00000025513	E1A binding protein p300 b.	Transcription factor AP-2 alpha.	0.439
LOC103468460	tfap2b	ENSPREP00000026558	ENSPREP00000023481	E1A binding protein p300 b.	Transcription factor AP-2 beta.	0.439
LOC103468460	tfap2c	ENSPREP00000026558	ENSPREP00000023993	E1A binding protein p300 b.	Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma).	0.439
LOC103468460	tfap2d	ENSPREP00000026558	ENSPREP00000023456	E1A binding protein p300 b.	Transcription factor AP-2 delta (activating enhancer binding protein 2 delta).	0.544
LOC103468460	tfap2e	ENSPREP00000026558	ENSPREP00000015078	E1A binding protein p300 b.	Transcription factor AP-2 epsilon.	0.439
LOC103471969	LOC103464091	ENSPREP00000020490	ENSPREP00000000408	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.	CREB binding protein a.	0.801
LOC103471969	LOC103468460	ENSPREP00000020490	ENSPREP00000026558	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.	E1A binding protein p300 b.	0.818
LOC103471969	LOC103482005	ENSPREP00000020490	ENSPREP00000030842	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a.	E1A binding protein p300 a.	0.818

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.831

expected number of edges:

11

PPI enrichment p-value:

0.00661

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

9 of 245

0.89

0.83

8.52e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

9 of 387

0.69

0.58

0.00044

GO:0016020

Membrane

10 of 698

0.48

0.38

0.0017

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2672

Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein

9 of 30

1.8

4.17

5.62e-13

CL:2670

Mixed, incl. Cobalt transport protein, and ABC transporter, CbiO/EcfA subunit

10 of 51

1.61

3.48

4.16e-13

CL:2722

Mixed, incl. Tricarboxylic acid biosynthetic process, and ABC transporter, CbiO/EcfA subunit

4 of 5

2.22

2.84

2.22e-06

CL:2668

Mixed, incl. ABC transporters, and DNA-binding HTH domain, TetR-type

11 of 111

1.32

2.33

7.15e-13

CL:2673

Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein

5 of 25

1.62

2.06

6.47e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

10 of 194

1.03

1.28

2.46e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

7 of 34

1.64

2.71

1.96e-08

GOCC:0005886

Plasma membrane

9 of 242

0.89

0.94

1.77e-06

GOCC:0032991

Protein-containing complex

8 of 382

0.64

0.52

0.0010

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0067

ATP-binding

6 of 228

0.74

0.41

0.0483

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR015856

ABC transporter, CbiO/EcfA subunit

6 of 10

2.1

3.62

1.55e-08

IPR017871

ABC transporter-like, conserved site

6 of 72

1.24

1.21

0.00022

IPR003439

ABC transporter-like, ATP-binding domain

6 of 90

1.15

1.04

0.00051

IPR003593

AAA+ ATPase domain

6 of 111

1.05

0.88

0.0012

IPR027417

P-loop containing nucleoside triphosphate hydrolase

6 of 224

0.75

0.41

0.0492

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

6 of 109

1.06

0.97

0.00040

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