STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gsk3aGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (438 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.924
LOC103477472
Glycogen synthase kinase binding protein.
    
 0.891
apc2
APC regulator of WNT signaling pathway 2.
    
 0.814
apc
APC regulator of WNT signaling pathway.
    
 0.814
LOC103456513
Uncharacterized protein.
   
 0.808
axin1
Axin 1.
   
 0.808
LOC103465321
Junction plakoglobin a.
    
 0.800
LOC103472282
Uncharacterized protein.
    
 0.800
fbxw11
F-box and WD repeat domain containing 11a.
    
 0.798
AXIN2
Axin 2.
   
 0.794
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.