STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)    
Predicted Functional Partners:
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
    
 0.958
cdk4
Cyclin-dependent kinase 4.
    
 0.958
LOC103466812
Cyclin D2, a; Belongs to the cyclin family.
    
 0.934
ccnd1
Cyclin D1; Belongs to the cyclin family.
    
 0.934
LOC103459164
Cyclin D2, b; Belongs to the cyclin family.
    
 0.934
Ccnd3
Cyclin D3; Belongs to the cyclin family.
    
 0.918
LOC103469340
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
    
 0.915
LOC103469079
Cyclin Dx; Belongs to the cyclin family.
    
 0.912
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.600
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.600
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.