STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ap1m2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (443 aa)    
Predicted Functional Partners:
ap1g1
AP-1 complex subunit gamma.
   
 0.990
LOC103478890
AP-1 complex subunit gamma.
   
 0.988
ap1b1
AP complex subunit beta.
   
 0.986
LOC103480134
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.967
gak
Cyclin G associated kinase.
   
 0.967
ap1s3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.967
LOC103479392
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.967
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.967
LOC103479779
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  
  
 
0.910
LOC103463064
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
  
  
 
0.910
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.