STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103473184G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)    
Predicted Functional Partners:
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.967
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
     
 0.947
LOC103468226
Casein kinase 1 gamma 2.
   
 
0.902
LOC103479254
Protein kinase domain-containing protein.
   
 
0.902
csnk1d
Casein kinase 1, delta b; Belongs to the protein kinase superfamily.
     
  0.900
LOC103468446
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
     
  0.900
arrb2
Arrestin, beta 2a.
   
 0.874
LOC103474633
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.710
LOC103461814
Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.710
ENSPREP00000030123
Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.710
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.