STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
farp2FERM, RhoGEF and pleckstrin domain protein 2. (1082 aa)    
Predicted Functional Partners:
nrp1
Neuropilin; Belongs to the neuropilin family.
     
 0.544
pip5k1c
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a.
     
 0.522
ENSPREP00000019117
PIPK domain-containing protein.
     
 0.522
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.507
LOC103464537
Macrophage stimulating 1 receptor a.
    
 0.507
mst1r
Macrophage stimulating 1 receptor b.
    
 0.507
rhof
Ras homolog family member F.
     
 0.462
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
     
 0.460
LOC103459228
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.
     
 0.427
sema3b
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.
     
 0.427
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.