STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vps26aVPS26, retromer complex component A. (304 aa)    
Predicted Functional Partners:
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.998
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.996
snx3
Sorting nexin 3.
   
 0.960
LOC103476205
Uncharacterized protein.
  
 
0.960
vps26b
VPS26, retromer complex component B.
  
 
0.960
tbc1d5
TBC1 domain family, member 5.
   
 
 0.909
SNX27
Sorting nexin 27.
   
 
 0.887
LOC103472691
Uncharacterized protein.
   
 
 0.887
snx2
Sorting nexin 2.
   
 
 0.806
LOC103472200
Sorting nexin 10a.
    
 0.779
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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