ldlr protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ldlr

Low density lipoprotein receptor a. (811 aa)

Predicted Functional Partners:

RELN

0.824

pcsk9

0.788

ldlrap1

0.704

LOC103478981

0.673

dab1

0.673

ENSPREP00000030577

0.648

mylip

0.574

ENSPREP00000015831

0.555

ENSPREP00000015870

0.555

ENSPREP00000015917

0.555

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000015831	ENSPREP00000015870	ENSPREP00000015831	ENSPREP00000015870	Uncharacterized protein.	Uncharacterized protein.	0.995
ENSPREP00000015831	ENSPREP00000015917	ENSPREP00000015831	ENSPREP00000015917	Uncharacterized protein.	EH domain-containing protein.	0.952
ENSPREP00000015831	ENSPREP00000030577	ENSPREP00000015831	ENSPREP00000030577	Uncharacterized protein.	Uncharacterized protein.	0.555
ENSPREP00000015831	LOC103478981	ENSPREP00000015831	ENSPREP00000005354	Uncharacterized protein.	DAB adaptor protein 1b.	0.940
ENSPREP00000015831	dab1	ENSPREP00000015831	ENSPREP00000031305	Uncharacterized protein.	DAB adaptor protein 1a.	0.940
ENSPREP00000015831	ldlr	ENSPREP00000015831	ENSPREP00000021780	Uncharacterized protein.	Low density lipoprotein receptor a.	0.555
ENSPREP00000015831	ldlrap1	ENSPREP00000015831	ENSPREP00000004477	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1b.	0.660
ENSPREP00000015870	ENSPREP00000015831	ENSPREP00000015870	ENSPREP00000015831	Uncharacterized protein.	Uncharacterized protein.	0.995
ENSPREP00000015870	ENSPREP00000015917	ENSPREP00000015870	ENSPREP00000015917	Uncharacterized protein.	EH domain-containing protein.	0.952
ENSPREP00000015870	ENSPREP00000030577	ENSPREP00000015870	ENSPREP00000030577	Uncharacterized protein.	Uncharacterized protein.	0.555
ENSPREP00000015870	LOC103478981	ENSPREP00000015870	ENSPREP00000005354	Uncharacterized protein.	DAB adaptor protein 1b.	0.940
ENSPREP00000015870	dab1	ENSPREP00000015870	ENSPREP00000031305	Uncharacterized protein.	DAB adaptor protein 1a.	0.940
ENSPREP00000015870	ldlr	ENSPREP00000015870	ENSPREP00000021780	Uncharacterized protein.	Low density lipoprotein receptor a.	0.555
ENSPREP00000015870	ldlrap1	ENSPREP00000015870	ENSPREP00000004477	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1b.	0.660
ENSPREP00000015917	ENSPREP00000015831	ENSPREP00000015917	ENSPREP00000015831	EH domain-containing protein.	Uncharacterized protein.	0.952
ENSPREP00000015917	ENSPREP00000015870	ENSPREP00000015917	ENSPREP00000015870	EH domain-containing protein.	Uncharacterized protein.	0.952
ENSPREP00000015917	ENSPREP00000030577	ENSPREP00000015917	ENSPREP00000030577	EH domain-containing protein.	Uncharacterized protein.	0.555
ENSPREP00000015917	LOC103478981	ENSPREP00000015917	ENSPREP00000005354	EH domain-containing protein.	DAB adaptor protein 1b.	0.940
ENSPREP00000015917	dab1	ENSPREP00000015917	ENSPREP00000031305	EH domain-containing protein.	DAB adaptor protein 1a.	0.940
ENSPREP00000015917	ldlr	ENSPREP00000015917	ENSPREP00000021780	EH domain-containing protein.	Low density lipoprotein receptor a.	0.555