STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adam17Pep_M12B_propep domain-containing protein. (290 aa)    
Predicted Functional Partners:
LOC103473440
Notch receptor 1a.
    
 0.936
notch1
Notch receptor 1b.
    
 0.936
ENSPREP00000021987
ADAM metallopeptidase domain 17b.
 
     0.932
LOC103468742
Notch receptor 3.
    
 0.909
LOC103463625
Notch receptor 2.
    
 0.907
LOC103458871
ADAM metallopeptidase domain 17a.
  
  
 
0.902
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.808
LOC103468846
TIMP metallopeptidase inhibitor 2b.
    
 0.548
LOC103481516
TIMP metallopeptidase inhibitor 2a.
    
 0.548
ngfr
Nerve growth factor receptor a (TNFR superfamily, member 16).
     
 0.504
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.