STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103480964Dickkopf_N domain-containing protein. (205 aa)    
Predicted Functional Partners:
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.951
Lrp6
LDL receptor related protein 6.
    
 0.951
dkk2
Dickkopf WNT signaling pathway inhibitor 2.
  
  
 
0.904
kremen1
Kringle containing transmembrane protein 1.
    
 0.741
LOC103476799
Dickkopf WNT signaling pathway inhibitor 1a.
     
0.555
ENSPREP00000027584
Low density lipoprotein receptor-related protein 6.
    
 0.532
CENPS
Centromere protein S.
    
 0.462
wscd1
WSC domain containing 1b.
    
 0.462
LOC103467230
Cortistatin.
    
 0.462
wscd2
WSC domain containing 2.
    
 0.462
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.