node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mcm5 | orc1 | ENSPREP00000022230 | ENSPREP00000001890 | Uncharacterized protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
Mcm5 | pcna | ENSPREP00000022230 | ENSPREP00000018020 | Uncharacterized protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.938 |
Mcm5 | prim1 | ENSPREP00000022230 | ENSPREP00000010453 | Uncharacterized protein. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.976 |
Mcm5 | prim2 | ENSPREP00000022230 | ENSPREP00000033224 | Uncharacterized protein. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.963 |
Mcm5 | rnaseh2a | ENSPREP00000022230 | ENSPREP00000022242 | Uncharacterized protein. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.804 |
Mcm5 | tyms | ENSPREP00000022230 | ENSPREP00000011292 | Uncharacterized protein. | Thymidylate synthetase. | 0.887 |
ndufab1 | pcna | ENSPREP00000028744 | ENSPREP00000018020 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.478 |
ndufab1 | rnaseh1 | ENSPREP00000028744 | ENSPREP00000018030 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.449 |
ndufab1 | rnaseh2a | ENSPREP00000028744 | ENSPREP00000022242 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.835 |
orc1 | Mcm5 | ENSPREP00000001890 | ENSPREP00000022230 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Uncharacterized protein. | 0.997 |
orc1 | pcna | ENSPREP00000001890 | ENSPREP00000018020 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.704 |
orc1 | prim1 | ENSPREP00000001890 | ENSPREP00000010453 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.921 |
orc1 | prim2 | ENSPREP00000001890 | ENSPREP00000033224 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.963 |
orc1 | rnaseh2a | ENSPREP00000001890 | ENSPREP00000022242 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.841 |
orc1 | tyms | ENSPREP00000001890 | ENSPREP00000011292 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Thymidylate synthetase. | 0.561 |
pcna | Mcm5 | ENSPREP00000018020 | ENSPREP00000022230 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uncharacterized protein. | 0.938 |
pcna | ndufab1 | ENSPREP00000018020 | ENSPREP00000028744 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.478 |
pcna | orc1 | ENSPREP00000018020 | ENSPREP00000001890 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.704 |
pcna | prim1 | ENSPREP00000018020 | ENSPREP00000010453 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.976 |
pcna | prim2 | ENSPREP00000018020 | ENSPREP00000033224 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.971 |