STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkbh4AlkB homolog 4, lysine demthylase. (278 aa)    
Predicted Functional Partners:
mettl4
Methyltransferase like 4; Belongs to the MT-A70-like family.
      
 0.649
Alkbh7
AlkB homolog 7.
   
  
 0.633
alkbh1
AlkB homolog 1, histone H2A dioxygenase.
   
  
 0.626
apex1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
 
      0.617
Alkbh6
AlkB homolog 6.
      
 0.560
jmjd4
Jumonji domain containing 4.
   
  
 0.558
n6amt1
N-6 adenine-specific DNA methyltransferase 1.
      
 0.550
dohh
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.
   
    0.550
klhl31
Kelch-like family member 31.
   
  
 0.550
d2hgdh
D-2-hydroxyglutarate dehydrogenase.
      
 0.536
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.