STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (939 aa)    
Predicted Functional Partners:
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.779
LOC103468393
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.672
pik3r3
Uncharacterized protein.
    
 0.653
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.653
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.653
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.650
LOC103464537
Macrophage stimulating 1 receptor a.
    
 0.650
mst1r
Macrophage stimulating 1 receptor b.
    
 0.650
LOC103470780
Uncharacterized protein.
    
 0.637
mras
Muscle RAS oncogene homolog.
   
 0.635
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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