STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plekha1Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (333 aa)    
Predicted Functional Partners:
rint1
RAD50 interactor 1.
    
 0.769
stx18
Syntaxin 18.
   
 0.743
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
 0.740
zw10
Zw10 kinetochore protein.
    
 0.717
nbas
Neuroblastoma amplified sequence.
   
 0.709
sec22a
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.552
LOC103479084
SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family.
   
 0.552
LOC103463624
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
 0.552
sec22c
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.552
LOC103460979
Coatomer protein complex, subunit gamma 2.
     
 0.502
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.