STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000023453P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (755 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin.
     
 0.683
LOC103472811
Uncharacterized protein.
     
 0.683
LOC103476384
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.560
ENSPREP00000030771
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.560
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.519
rxfp1
Relaxin family peptide receptor 1.
   
 0.519
rxfp2
Relaxin family peptide receptor 2a.
   
 0.519
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
   
 0.519
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.497
LOC103475119
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.468
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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