STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sorl1Sortilin-related receptor, L(DLR class) A repeats containing. (2086 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.947
app
Amyloid beta (A4) precursor protein a.
    
 0.903
LOC103459816
Amyloid beta (A4) precursor protein b.
    
 0.903
LOC103481937
Uncharacterized protein.
    
 
 0.893
LOC103464672
Uncharacterized protein.
    
 
 0.893
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.893
LOC103474743
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.772
cltc
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.772
cltcl1
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.772
LOC103477848
Apolipoprotein Eb.
    
 0.768
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.