STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)    
Predicted Functional Partners:
hyou1
Hypoxia up-regulated 1.
  
 
0.994
manf
Mesencephalic astrocyte-derived neurotrophic factor.
   
 
 0.988
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.987
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
 
 0.985
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10.
  
 0.985
sil1
SIL1 nucleotide exchange factor.
   
 
 0.973
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.968
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.958
sec63
SEC63 homolog, protein translocation regulator.
  
 
 0.957
eif2ak3
Eukaryotic translation initiation factor 2-alpha kinase 3.
   
 0.953
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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